Production and Technology

IMUNA PHARM, a.s. continuously innovates its production capacities and technologies. At present, it possesses the technological means to manufacture products in 5 areas:

  • Liquid pharmaceuticals (infusion, irrigation and dialysis solution)
  • Immunopreparations
  • Liquid pharmaceuticals
  • Dietary and nutritional supplements
  • Medical devices

The following equipment is available:

GHIBLI 100 Fluid Bed Drying Tower

  • for wet granulation and fluid product drying
  • max. amount of granulate processed/dried in one cycle = c. 220 liters / 4 hrs.

Cyclops Aries Maxi Homogenizer

  • powdered form homogenizer
  • 1000-liter bin
  • max. amount of homogenized material = c. 600 liters

Kilian E 150 Plus Tablet Press

  • die diameter: 13 mm; dimensions: 11–16 mm
  • maximum output = 162 800 tablets per hour
  • optimum output = 60 000–100 000 tablets per hour, depending on the type of material processed into tablets
  • parameters can be customized using modification parts

Duplicator Boiler

  • for the preparation of solutions
  • boiler heated by technical steam
  • volume = 500 liters

Mixer with Temperature Control

  • for the preparation of solutions
  • boiler heated by hot water
  • volume = 1000 liters

Niro Atomizer Spray Drying Tower

  • drying solutions at high temperatures, preparing powdered product forms
  • output: the tower dries c. 30 liters of solution per hour
  • spray drying technology

Spindle homogenizer

  • homogenization of powdered drug forms
  • homogenizer volume = c. 400 liters

IMA Blister and Cartoning Machine

  • maximum output = 220 blisters per minute, or 120 packagings per minute
  • PVC, aluminum foil
  • parameters can be customized using modification parts

Water Management

  • PW water – RO O1-1/EDI- 300 Eurowater reverse osmosis capacity (300 liters per hour, 2000-liter magazine)
  • WFI –Steris Finn-Aqua 250-T-4-S7 distillation apparatus capacity (300 liters per hour, 2000-liter magazine)

ROTA RWM 300 Washing Machine

  • 18 000 units per hour capacity
  • washes 1 ml, 2 ml, and 5 ml ampoules and vials 2R/4R

ROTA R941/MA-G Ampoule Filling Machine

  • 12 000 units per hour capacity.
  • fills 1 ml, 2 ml, and 5 ml ampoule
  • vials – 2R, 4R

ROTA FLR 300 Vial Filler and Closer

  • vials – 2R, 4R
  • 18 000 units per hour capacity

CHRIST EPSILON 2-45DS Lyophilisation Machine

  • Capacity of 16 000 units / 2 ml ampoules in a bed area of 3.2 m2

Homogenization Boiler

  • Capacity of 100 liters

Manufacturing Spaces

  • Clean spaces in Class A, Class B and Class C
  • Continuous particle monitoring in Class A and B spaces

EISAI AIM 287 Optical Inspection Machine for Ampoules

  • Optical inspection of ampoules with solution (vaccine solvent)

FRIGERA SZ 700 Shock Freezer

  • Shock freezing instrument for ampoules with vaccine (-80°C / -60°C)

Other Technological Equipment

  • GILOWY washing machine for laboratory glassware
  • STERIVAP HP IL steam stabilizers – type SPHP(BMT)
  • CO2 incubators, biohazard – laboratory
  • Microbiological incubators
  • Cooling boxes (2-8°C), freezer boxes (-20±5)°C, (-50±5)°C
  • VENTICELL Hot-air sterilizers for glassware depyrogenization (BMT)
  • Technical facilities: air conditioning units, technical and clean steam generators (Steris Finn-Aqua 450-T)
  • Compressed air production equipment
  • Power backup
  • Daikin cooling aggregator

Gallery

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